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Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP) Obesity (Silver Spring) 2012;20(2):330342

however, as per the American Academy of Dermatology (AAD) guidelines, there is hesitancy to combine oral isotretinoin with NAL therapies

Over-the-counter antidiarrheal medications like loperamide or fiber supplements and osmotic laxatives may be appropriate for short-term use, but you should discuss these options with your healthcare provider before starting them to ensure safe and effective management

For nausea, she recommends that patients eat slowly and stop eating when full

Magnesium citrate at 200 to 400 mg before bed acts as a gentle osmotic laxative